Mitochondrial DNA haplogroups and type 2 diabetes: a study of 897 cases and 1010 controls.

Mitochondrial DNA haplogroups and type 2 diabetes: a study of 897 cases and 1010 controls.

Mitochondria play a central role in the secretion of insulin by pancreatic beta-cells, and pathogenic mutations of mitochondrial DNA (mtDNA) can cause diabetes. The aetiology of type 2 diabetes has a strong genetic component, raising the possibility that genetic variants of mtDNA alter the risk of d...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Chinnery, P, Mowbray, C, Patel, S, Elson, J, Sampson, M, Hitman, G, McCarthy, M, Hattersley, A, Walker, M
Format:	Journal article
Sprache:	English
Veröffentlicht:	2007

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