Mitochondrial DNA haplogroups and type 2 diabetes: a study of 897 cases and 1010 controls.

Mitochondrial DNA haplogroups and type 2 diabetes: a study of 897 cases and 1010 controls.

Mitochondria play a central role in the secretion of insulin by pancreatic beta-cells, and pathogenic mutations of mitochondrial DNA (mtDNA) can cause diabetes. The aetiology of type 2 diabetes has a strong genetic component, raising the possibility that genetic variants of mtDNA alter the risk of d...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Chinnery, P, Mowbray, C, Patel, S, Elson, J, Sampson, M, Hitman, G, McCarthy, M, Hattersley, A, Walker, M
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2007

Những quyển sách tương tự

Role of the mitochondrial DNA 16184-16193 poly-C tract in type 2 diabetes.
Bằng: Chinnery, P, et al.
Được phát hành: (2005)

Mitochondrial DNA haplogroups and risk of transient ischaemic attack and ischaemic stroke: a genetic association study.
Bằng: Chinnery, P, et al.
Được phát hành: (2010)

Mitochondrial DNA haplogroup H structure in North Africa
Bằng: Dzimiri Nduna, et al.
Được phát hành: (2009-02-01)

Extracellular vesicle mitochondrial DNA levels are associated with race and mitochondrial DNA haplogroup
Bằng: Anjali M. Byappanahalli, et al.
Được phát hành: (2024-01-01)

Parental diabetes status reveals association of mitochondrial DNA haplogroup J1 with type 2 diabetes
Bằng: Wainstein Julio, et al.
Được phát hành: (2009-06-01)

GENETIC DIVERSITY OF MITOCHONDRIAL DNA HAPLOGROUPS IN THE DON HORSE BREED
Bằng: Liudmila A. Khrabrova, et al.
Được phát hành: (2023-08-01)

Mitochondrial DNA Haplogroups and Variants Predispose to Chagas Disease Cardiomyopathy
Bằng: Frédéric Gallardo, et al.
Được phát hành: (2023-12-01)

A Spatio-Temporal Analysis of Mitochondrial DNA Haplogroup I
Bằng: Revesz Peter Z.
Được phát hành: (2016-01-01)

Differential effects of cisplatin on cybrid cells with varying mitochondrial DNA haplogroups
Bằng: Sina Abedi, et al.
Được phát hành: (2020-10-01)

Heritability estimates for beta cell function and features of the insulin resistance syndrome in UK families with an increased susceptibility to type 2 diabetes.
Bằng: Mills, G, et al.
Được phát hành: (2004)

Functional differences between mitochondrial haplogroup T and haplogroup H in HEK293 cybrid cells.
Bằng: Edith E Mueller, et al.
Được phát hành: (2012-01-01)

Mitochondrial DNA haplogroups in early-onset Alzheimer's disease and frontotemporal lobar degeneration
Bằng: Hinttala Reetta, et al.
Được phát hành: (2010-02-01)

Reduced beta cell function in offspring of mothers with young-onset type 2 diabetes.
Bằng: Singh, R, et al.
Được phát hành: (2006)

Reduced beta cell function in offspring of mothers with young onset type 2 diabetes
Bằng: Singh, R, et al.
Được phát hành: (2005)

Young-onset type 2 diabetes families are the major contributors to genetic loci in the Diabetes UK Warren 2 genome scan and identify putative novel loci on chromosomes 8q21, 21q22, and 22q11.
Bằng: Frayling, T, et al.
Được phát hành: (2003)

Diversity of Mitochondrial DNA Haplogroups and Their Association with Bovine Antral Follicle Count
Bằng: Hongfei Liu, et al.
Được phát hành: (2022-09-01)

Mitochondrial DNA haplogroup analysis in Saudi Arab patients with multiple sclerosis.
Bằng: Ghada Al-Kafaji, et al.
Được phát hành: (2022-01-01)

Mitochondrial DNA haplogroup analysis in Saudi Arab patients with multiple sclerosis
Bằng: Ghada Al-Kafaji, et al.
Được phát hành: (2022-01-01)

Mitochondrial DNA Haplogroups and the Risk of Sporadic Parkinson′s Disease in Han Chinese
Bằng: Ya-Fang Chen, et al.
Được phát hành: (2015-01-01)

Mitochondrial DNA Haplogroup Related to the Prevalence of <i>Helicobacter pylori</i>
Bằng: Yeonmi Lee, et al.
Được phát hành: (2021-09-01)

Association of mitochondrial DNA polymorphisms and/or haplogroups with elite Japanese athlete status
Bằng: Noriyuki Fuku, et al.
Được phát hành: (2013-04-01)

The Q2 mitochondrial haplogroup in Oceania.
Bằng: Chris A Corser, et al.
Được phát hành: (2012-01-01)

Mitochondrial DNA haplogroup T is associated with coronary artery disease and diabetic retinopathy: a case control study
Bằng: Kofler Barbara, et al.
Được phát hành: (2009-04-01)

Differential modulation of cancer‐related genes by mitochondrial DNA haplogroups and the STING DNA sensing system
Bằng: Kevin Schneider, et al.
Được phát hành: (2022-10-01)

Assessment of the role of genetic variation in the transient neonatal diabetes (TNDM) region on chromosome 6q24 in type 2 diabetes: a comparative genomic and haplotype approach
Bằng: Gloyn, A, et al.
Được phát hành: (2005)

Role of the D76N polymorphism of insulin promoter factor-1 in predisposing to Type 2 diabetes.
Bằng: Owen, K, et al.
Được phát hành: (2004)

No evidence of association of ENPP1 variants with type 2 diabetes or obesity in a study of 8,089 U.K. Caucasians.
Bằng: Weedon, M, et al.
Được phát hành: (2006)

Mitochondrial DNA haplogroup background affects LHON, but not suspected LHON, in Chinese patients.
Bằng: A-Mei Zhang, et al.
Được phát hành: (2011-01-01)

Mitochondrial DNA (mtDNA) haplogroups in 1526 unrelated individuals from 11 Departments of Colombia
Bằng: Juan J. Yunis, et al.
Được phát hành: (2013-01-01)

Mitochondrial DNA (mtDNA) haplogroups and serum levels of anti-oxidant enzymes in patients with osteoarthritis
Bằng: Fernandez-Moreno Mercedes, et al.
Được phát hành: (2011-11-01)

Common variation in the LMNA gene increases susceptibility to type 2 diabetes
Bằng: Owen, K, et al.
Được phát hành: (2006)

Examining the relationships between the Pro12Ala variant in PPARG and Type 2 diabetes-related traits in UK samples.
Bằng: Zeggini, E, et al.
Được phát hành: (2005)

Mitochondrial super-haplogroup U diversity in Serbians
Bằng: Slobodan Davidovic, et al.
Được phát hành: (2017-07-01)

The mitochondrial ancestor of bonobos and the origin of their major haplogroups.
Bằng: Hiroyuki Takemoto, et al.
Được phát hành: (2017-01-01)

Common variations in the ALMS1 gene do not contribute to susceptibility to type 2 diabetes in a large white UK population.
Bằng: Patel, S, et al.
Được phát hành: (2006)

Population expansion in the North African Late Pleistocene signalled by mitochondrial DNA haplogroup U6
Bằng: Costa Marta D, et al.
Được phát hành: (2010-12-01)

Complex spatio-temporal distribution and genomic ancestry of mitochondrial DNA haplogroups in 24,216 Danes.
Bằng: Jonas Bybjerg-Grauholm, et al.
Được phát hành: (2018-01-01)

Functional variation in VEGF is not associated with type 2 diabetes in a United Kingdom Caucasian population.
Bằng: Freathy, R, et al.
Được phát hành: (2006)

Evaluation of D-loop hypervariable region I variations, haplogroups and copy number of mitochondrial DNA in Bangladeshi population with type 2 diabetes
Bằng: Sajoy Kanti Saha, et al.
Được phát hành: (2021-07-01)

Origin and post-glacial dispersal of mitochondrial DNA haplogroups C and D in northern Asia.
Bằng: Miroslava Derenko, et al.
Được phát hành: (2010-12-01)