The assembly of large BACs by in vivo recombination.

We have developed a method for recombining bacterial artificial chromosomes (BACs) and P1 artificial chromosomes (PACs) containing large genomic DNA fragments into a single vector using the Cre-lox recombination system from bacteriophage P1 in vivo. This overcomes the limitations of in vitro methods...

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Hlavní autoři: Mejía, J, Larin, Z
Médium: Journal article
Jazyk:English
Vydáno: 2000

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