The role of DNA exonucleases in protecting genome stability and their impact on ageing.

Exonucleases are key enzymes involved in many aspects of cellular metabolism and maintenance and are essential to genome stability, acting to cleave DNA from free ends. Exonucleases can act as proofreaders during DNA polymerisation in DNA replication, to remove unusual DNA structures that arise from...

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Bibliographic Details
Main Authors: Mason, P, Cox, L
Format: Journal article
Language:English
Published: Springer Verlag 2011

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