Examining the relationships between the Pro12Ala variant in PPARG and Type 2 diabetes-related traits in UK samples.
AIMS: The Pro12Ala polymorphism in the PPARG gene alters amino acid sequence and has shown consistent association with susceptibility to Type 2 diabetes in several populations. The present study makes use of large, well-characterized case-control resources to enhance understanding of this susceptibi...
Autores principales: | Zeggini, E, Parkinson, JR, Halford, S, Owen, K, Walker, M, Hitman, G, Levy, J, Sampson, M, Frayling, T, Hattersley, A, McCarthy, M |
---|---|
Formato: | Journal article |
Lenguaje: | English |
Publicado: |
2005
|
Ejemplares similares
-
Interaction of PPARG Pro12Ala with dietary fat influences plasma lipids in subjects at cardiometabolic risk.
por: Alsaleh, A, et al.
Publicado: (2011) -
Association studies of insulin receptor substrate 1 gene (IRS1) variants in type 2 diabetes samples enriched for family history and early age of onset.
por: Zeggini, E, et al.
Publicado: (2004) -
Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes.
por: Gloyn, A, et al.
Publicado: (2003) -
Large-scale association studies of variants in genes encoding the pancreatic beta-cell K-ATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes
por: Gloyn, A, et al.
Publicado: (2003) -
Large-scale association studies of candidate genes and their interactions in Type 2 diabetes
por: Zeggini, E, et al.
Publicado: (2004)