Snake venomics of African spitting cobras: toxin composition and assessment of congeneric cross-reactivity of the pan-African EchiTAb-Plus-ICP antivenom by antivenomics and neutralization approaches.

Snake venomics of African spitting cobras: toxin composition and assessment of congeneric cross-reactivity of the pan-African EchiTAb-Plus-ICP antivenom by antivenomics and neutralization approaches.

Venomic analysis of the venoms of Naja nigricollis, N. katiensis, N. nubiae, N. mossambica, and N. pallida revealed similar compositional trends. The high content of cytotoxins and PLA(2)s may account for the extensive tissue necrosis characteristic of the envenomings by these species. The high abun...

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Bibliographic Details
Main Authors: Petras, D, Sanz, L, Segura, A, Herrera, M, Villalta, M, Solano, D, Vargas, M, León, G, Warrell, D, Theakston, R, Harrison, R, Durfa, N, Nasidi, A, Gutiérrez, J, Calvete, J
Format: Journal article
Language:English
Published: 2011

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