Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis.

Recent findings in the animal model for multiple sclerosis (MS), experimental autoimmune encephalomyelitis, implicate a novel CD4+ T-cell subset (TH17), characterized by the secretion of interleukin-17 (IL-17), in disease pathogenesis. To elucidate its role in MS, brain tissues from patients with MS...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Tzartos, J, Friese, M, Craner, M, Palace, J, Newcombe, J, Esiri, M, Fugger, L
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2008