Fundamental biochemistry of the early N-glycosylation pathway

<p>Oligosaccharides destined for use as N-linked glycans are synthesised on phosphorylated dolichols in the endoplasmic reticulum (ER) by a series of glycosyltransferase enzymes known as ALG proteins. Mutations in any of these synthesis enzymes can lead to severe, multisystem syndromes known a...

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Autore principale: Eddershaw, A
Altri autori: Dong, Y
Natura: Tesi
Lingua:English
Pubblicazione: 2024
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