Fundamental biochemistry of the early N-glycosylation pathway

<p>Oligosaccharides destined for use as N-linked glycans are synthesised on phosphorylated dolichols in the endoplasmic reticulum (ER) by a series of glycosyltransferase enzymes known as ALG proteins. Mutations in any of these synthesis enzymes can lead to severe, multisystem syndromes known a...

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Detalles Bibliográficos
Autor Principal: Eddershaw, A
Outros autores: Dong, Y
Formato: Thesis
Idioma:English
Publicado: 2024
Subjects: