Fundamental biochemistry of the early N-glycosylation pathway

<p>Oligosaccharides destined for use as N-linked glycans are synthesised on phosphorylated dolichols in the endoplasmic reticulum (ER) by a series of glycosyltransferase enzymes known as ALG proteins. Mutations in any of these synthesis enzymes can lead to severe, multisystem syndromes known a...

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Bibliografski detalji
Glavni autor: Eddershaw, A
Daljnji autori: Dong, Y
Format: Disertacija
Jezik:English
Izdano: 2024
Teme: