Carbapenems versus other beta-lactams in treating severe infections in intensive care: a systematic review of randomised controlled trials.

Carbapenems versus other beta-lactams in treating severe infections in intensive care: a systematic review of randomised controlled trials.

Carbapenems have not been comprehensively compared in clinical trials with fourth-generation cephalosporins (4GC) and antipseudomonal penicillins (APP) in the treatment of severe infections (SI) and febrile neutropenia (FN). A systematic review of CENTRAL, EMBASE, MEDLINE and JICST-EPlus for randomi...

Full description

Bibliographic Details
Main Authors:	Edwards, S, Clarke, M, Wordsworth, S, Emmas, C
Format:	Journal article
Language:	English
Published:	2008

Similar Items

Carbapenems versus other beta-lactams in the treatment of hospitalised patients with infection: a mixed treatment comparison.
by: Edwards, S, et al.
Published: (2009)

In-vitro activity of carbapenem antibiotics against beta-lactam susceptible and resistant strains of Burkholderia pseudomallei.
by: Smith, MD, et al.
Published: (1996)

Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis
by: Abdul-Aziz, M.H., et al.
Published: (2016)

Systematic review comparing meropenem with imipenem plus cilastatin in the treatment of severe infections.
by: Edwards, S, et al.
Published: (2005)

Reversible acylation of elastase by gamma-lactam analogues of beta-lactam inhibitors
by: Westwood, N, et al.
Published: (1997)

The use of polymyxins to treat carbapenem resistant infections in neonates and children
by: Thomas, R, et al.
Published: (2018)

THE ASYMMETRIC-SYNTHESIS OF BETA-LACTAMS
by: Blackburn, B, et al.
Published: (1987)

The enzymes of beta-lactam biosynthesis
by: Hamed, R, et al.
Published: (2013)

The origin of the beta-lactam carbons of clavulanic acid
by: Thirkettle, J, et al.
Published: (1997)

beta-lactam synthetase: Implications for beta-lactamase evolution
by: McNaughton, H, et al.
Published: (1998)

Enzymatic synthesis of monocyclic beta-lactams.
by: Sleeman, M, et al.
Published: (2002)

Interactions of hydrolyzed β-lactams with the L1 metallo-β-lactamase: Crystallography supports stereoselective binding of cephem/carbapenem products
by: Hinchliffe, P, et al.
Published: (2023)

Indirect comparisons of treatments based on systematic reviews of randomised controlled trials.
by: Edwards, S, et al.
Published: (2009)

Use of penicillin MICs to predict in vitro activity of other beta-lactam antimicrobial agents against Streptococcus pneumoniae.
by: Brueggemann, A, et al.
Published: (2001)

STEREOSELECTIVE PREPARATION OF BETA-AMINO-ACYL IRON COMPLEXES FOR BETA-LACTAM SYNTHESIS
by: Broadley, K, et al.
Published: (1984)

Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase.
by: Ho, Siaw Eng, et al.
Published: (2002)

Risk factors and outcomes of carbapenem-resistant gram negative bloodstream infection in Intensive Care Unit, HUSM
by: Aziz, Rozila
Published: (2015)

Biosynthesis of carbapenem antibiotics: new carbapenam substrates for carbapenem synthase (CarC).
by: Sleeman, M, et al.
Published: (2004)

Understanding Beta-Lactam-Induced Lysis at the Single-Cell Level
by: Wong, Felix, et al.
Published: (2021)

Exploring and enhancing context-dependent beta-lactam antibiotic efficacy
by: Bening, Sarah Christine.
Published: (2021)

Brexpiprazole versus placebo or other antidepressive agents for treating depression
by: Ralovska, S, et al.
Published: (2021)

The enzymology of clavam and carbapenem biosynthesis.
by: Kershaw, N, et al.
Published: (2005)

Selective deprotection strategies to N-(alpha-methylbenzyl)-beta-amino esters and derived beta lactams
by: Davies, S, et al.
Published: (1998)

Pseudomonas pseudomallei resistance to beta-lactam antibiotics due to alterations in the chromosomally encoded beta-lactamase.
by: Godfrey, A, et al.
Published: (1991)

Personalised randomised controlled trial designs – a new paradigm to define optimal treatments for carbapenem-resistant infections
by: Walker, AS, et al.
Published: (2021)

Continuous beta-lactam infusion in critically ill patients: the clinical evidence
by: Abdul Aziz, Mohd. Hafiz, et al.
Published: (2012)

Stereospecific total synthesis of beta-lactam antibiotics from peptide precursors.
by: Christie, Michael Allen.
Published: (2024)

Combination Versus Monotherapy for Carbapenem-Resistant Acinetobacter Species Serious Infections: A Prospective IPTW Adjusted Cohort Study
by: Manesh, A, et al.
Published: (2024)

Application of zinc-and aluminum ester :: Enolates in the stereoselective synthesis of Beta-lactam antibiotics
by: , STEEN, Frederik Hendrik van der, et al.
Published: (1991)

Antecedent carbapenem exposure as a risk factor for non-carbapenemase-producing carbapenem-resistant enterobacteriaceae and carbapenemase-producing enterobacteriaceae
by: Marimuthu, Kalisvar, et al.
Published: (2020)

Biochemistry of peptide antibiotics : recent advances in the biotechnology of beta-lactams and microbial bioactive peptides /
by: Kleinkauf, Horst, et al.
Published: (1990)

Crystal structure of carbapenem synthase (CarC).
by: Clifton, I, et al.
Published: (2003)

Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial.
by: Dondorp, A, et al.
Published: (2005)

Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial
by: Faiz, M, et al.
Published: (2005)

The biosynthesis of β-lactams
by: Goh, K, et al.
Published: (1993)

Lactam terpolymer membranes /
by: 211961 Carden, Joseph A., et al.

Lactam terpolymer membranes /
by: 211961 Carden, Joseph A., et al.

Evaluation of pre-treated healthcare wastes during COVID-19 pandemic reveals pathogenic microbiota, antibiotics residues, and antibiotic resistance genes against beta-lactams
by: Siew, Shing Wei, et al.
Published: (2023)

Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex.
by: Wilmouth, R, et al.
Published: (1998)

Is the hospital water environment a reservoir for carbapenem-resistant organisms causing hospital-acquired infections? A systematic review of the literature
by: Kizny-Gordon, A, et al.
Published: (2017)