OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL Responses after virus infection.

OX40, a member of the TNF receptor superfamily, is expressed on activated T cells and implicated in stimulation of T cells and T-dependent humoral responses. We generated OX40-/- mice and found that the formation of extrafollicular plasma cells, germinal centers, and antibody responses was independe...

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Príomhchruthaitheoirí: Kopf, M, Ruedl, C, Schmitz, N, Gallimore, A, Lefrang, K, Ecabert, B, Odermatt, B, Bachmann, M
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 1999

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