Sputum IL-5 concentration is associated with a sputum eosinophilia and attenuated by corticosteroid therapy in COPD.

Sputum IL-5 concentration is associated with a sputum eosinophilia and attenuated by corticosteroid therapy in COPD.

BACKGROUND: Airway inflammation in chronic obstructive pulmonary disease (COPD) is predominately neutrophilic, but some subjects demonstrate eosinophilic airway inflammation. Whether these inflammatory phenotypes have differential cytokine and chemokine expression is unknown. OBJECTIVES: To assess t...

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Bibliographic Details
Main Authors: Bafadhel, M, Saha, S, Siva, R, McCormick, M, Monteiro, W, Rugman, P, Dodson, P, Pavord, I, Newbold, P, Brightling, C
Format: Journal article
Language:English
Published: 2009

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