Selected contribution: High-altitude natives living at sea level acclimatize to high altitude like sea-level natives.

Sea-level (SL) natives acclimatizing to high altitude (HA) increase their acute ventilatory response to hypoxia (AHVR), but HA natives have values for AHVR below those for SL natives at SL (blunting). HA natives who live at SL retain some blunting of AHVR and have more marked blunting to sustained (...

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Main Authors: Rivera-Ch, M, Gamboa, A, Léon-Velarde, F, Palacios, J, O'Connor, D, Robbins, P
Formato: Journal article
Idioma:English
Publicado em: 2003
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author Rivera-Ch, M
Gamboa, A
Léon-Velarde, F
Palacios, J
O'Connor, D
Robbins, P
author_facet Rivera-Ch, M
Gamboa, A
Léon-Velarde, F
Palacios, J
O'Connor, D
Robbins, P
author_sort Rivera-Ch, M
collection OXFORD
description Sea-level (SL) natives acclimatizing to high altitude (HA) increase their acute ventilatory response to hypoxia (AHVR), but HA natives have values for AHVR below those for SL natives at SL (blunting). HA natives who live at SL retain some blunting of AHVR and have more marked blunting to sustained (20-min) hypoxia. This study addressed the question of what happens when HA natives resident at SL return to HA: do they acclimatize like SL natives or revert to the characteristics of HA natives? Fifteen HA natives resident at SL were studied, together with 15 SL natives as controls. Air-breathing end-tidal Pco(2) and AHVR were determined at SL. Subjects were then transported to 4,300 m, where these measurements were repeated on each of the following 5 days. There were no significant differences in the magnitude or time course of the changes in end-tidal Pco(2) and AHVR between the two groups. We conclude that HA natives normally resident at SL undergo ventilatory acclimatization to HA in the same manner as SL natives.
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spelling oxford-uuid:c11e08b9-98c7-47e9-a3eb-a31e9a21a9a22022-03-27T05:59:12ZSelected contribution: High-altitude natives living at sea level acclimatize to high altitude like sea-level natives.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:c11e08b9-98c7-47e9-a3eb-a31e9a21a9a2EnglishSymplectic Elements at Oxford2003Rivera-Ch, MGamboa, ALéon-Velarde, FPalacios, JO'Connor, DRobbins, PSea-level (SL) natives acclimatizing to high altitude (HA) increase their acute ventilatory response to hypoxia (AHVR), but HA natives have values for AHVR below those for SL natives at SL (blunting). HA natives who live at SL retain some blunting of AHVR and have more marked blunting to sustained (20-min) hypoxia. This study addressed the question of what happens when HA natives resident at SL return to HA: do they acclimatize like SL natives or revert to the characteristics of HA natives? Fifteen HA natives resident at SL were studied, together with 15 SL natives as controls. Air-breathing end-tidal Pco(2) and AHVR were determined at SL. Subjects were then transported to 4,300 m, where these measurements were repeated on each of the following 5 days. There were no significant differences in the magnitude or time course of the changes in end-tidal Pco(2) and AHVR between the two groups. We conclude that HA natives normally resident at SL undergo ventilatory acclimatization to HA in the same manner as SL natives.
spellingShingle Rivera-Ch, M
Gamboa, A
Léon-Velarde, F
Palacios, J
O'Connor, D
Robbins, P
Selected contribution: High-altitude natives living at sea level acclimatize to high altitude like sea-level natives.
title Selected contribution: High-altitude natives living at sea level acclimatize to high altitude like sea-level natives.
title_full Selected contribution: High-altitude natives living at sea level acclimatize to high altitude like sea-level natives.
title_fullStr Selected contribution: High-altitude natives living at sea level acclimatize to high altitude like sea-level natives.
title_full_unstemmed Selected contribution: High-altitude natives living at sea level acclimatize to high altitude like sea-level natives.
title_short Selected contribution: High-altitude natives living at sea level acclimatize to high altitude like sea-level natives.
title_sort selected contribution high altitude natives living at sea level acclimatize to high altitude like sea level natives
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