Gene expression profiling in single cells from the pancreatic islets of Langerhans reveals lognormal distribution of mRNA levels.

The transcriptional machinery in individual cells is controlled by a relatively small number of molecules, which may result in stochastic behavior in gene activity. Because of technical limitations in current collection and recording methods, most gene expression measurements are carried out on popu...

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Autors principals: Bengtsson, M, Ståhlberg, A, Rorsman, P, Kubista, M
Format: Journal article
Idioma:English
Publicat: 2005