H4K20me0 recognition by BRCA1–BARD1 directs homologous recombination to sister chromatids

H4K20me0 recognition by BRCA1–BARD1 directs homologous recombination to sister chromatids

Genotoxic DNA double-strand breaks (DSBs) can be repaired by error-free homologous recombination (HR) or mutagenic non-homologous end-joining1. HR supresses tumorigenesis1, but is restricted to the S and G2 phases of the cell cycle when a sister chromatid is present2. Breast cancer type 1 susceptibi...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Nakamura, K, Saredi, G, Becker, J, Foster, B, Nguyen, N, Beyer, T, Cesa, L, Faull, P, Lukauskas, S, Frimurer, T, Chapman, J, Bartke, T, Groth, A
التنسيق: Journal article
اللغة:English
منشور في: Springer Nature 2019

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