Loss of FHIT function in lung cancer and preinvasive bronchial lesions.

Loss of FHIT function in lung cancer and preinvasive bronchial lesions.

We previously cloned and characterized the tumor suppressor gene FHIT (fragile histidine triad) at chromosome 3p14.2 and found that this gene is altered by deletions in human tumors, including lung cancer. To assess the frequency and specificity of inactivation and its relevance in a clinical settin...

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Bibliographic Details
Main Authors: Sozzi, G, Pastorino, U, Moiraghi, L, Tagliabue, E, Pezzella, F, Ghirelli, C, Tornielli, S, Sard, L, Huebner, K, Pierotti, M, Croce, C, Pilotti, S
Format: Journal article
Language:English
Published: 1998

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