Evolution of the human immunodeficiency virus envelope gene is dominated by purifying selection.

Evolution of the human immunodeficiency virus envelope gene is dominated by purifying selection.

The evolution of the human immunodeficiency virus (HIV-1) during chronic infection involves the rapid, continuous turnover of genetic diversity. However, the role of natural selection, relative to random genetic drift, in governing this process is unclear. We tested a stochastic model of genetic dri...

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Bibliographic Details
Main Authors:	Edwards, C, Holmes, E, Pybus, O, Wilson, D, Viscidi, R, Abrams, E, Phillips, R, Drummond, A
Format:	Journal article
Language:	English
Published:	2006

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