Evolution of the human immunodeficiency virus envelope gene is dominated by purifying selection.

The evolution of the human immunodeficiency virus (HIV-1) during chronic infection involves the rapid, continuous turnover of genetic diversity. However, the role of natural selection, relative to random genetic drift, in governing this process is unclear. We tested a stochastic model of genetic dri...

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Détails bibliographiques
Auteurs principaux: Edwards, C, Holmes, E, Pybus, O, Wilson, D, Viscidi, R, Abrams, E, Phillips, R, Drummond, A
Format: Journal article
Langue:English
Publié: 2006