MHC binding affects the dynamics of different T-cell receptors in different ways

MHC binding affects the dynamics of different T-cell receptors in different ways

Detalhes bibliográficos
Main Authors:	Knapp, B, Van Der Merwe, P, Dushek, O, Deane, C
Formato:	Journal article
Idioma:	English
Publicado em:	Public Library of Science 2019

Registos relacionados

MHC binding affects the dynamics of different T-cell receptors in different ways.
Por: Bernhard Knapp, et al.
Publicado em: (2019-09-01)

The contribution of major histocompatibility complex contacts to the affinity and kinetics of T cell receptor binding
Por: Zhang, H, et al.
Publicado em: (2016)

Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time.
Por: Aleksic, M, et al.
Publicado em: (2010)

Analysis of serial engagement and peptide-MHC transport in T cell receptor microclusters.
Por: Dushek, O, et al.
Publicado em: (2008)

T cell receptor and coreceptor CD8 alphaalpha bind peptide-MHC independently and with distinct kinetics.
Por: Wyer, JR, et al.
Publicado em: (1999)

Mechanisms for T cell receptor triggering.
Por: Van Der Merwe, P, et al.
Publicado em: (2011)

TCR–pMHC kinetics under force in a cell-free system show no intrinsic catch bond, but a minimal encounter duration before binding
Por: Limozin, L, et al.
Publicado em: (2019)

Fluctuations in T cell receptor and pMHC interactions regulate T cell activation
Por: Egan, JR, et al.
Publicado em: (2022)

Fluctuations in T cell receptor and pMHC interactions regulate T cell activation
Por: Egan, JR, et al.
Publicado em: (2022)

Kinetics and mechanics of two-dimensional interactions between T cell receptors and different activating ligands.
Por: Robert, P, et al.
Publicado em: (2012)

T-cell receptor triggering is critically dependent on the dimensions of its peptide-MHC ligand.
Por: Choudhuri, K, et al.
Publicado em: (2005)

Mechanical modulation of receptor-ligand interactions at cell-cell interfaces.
Por: Allard, J, et al.
Publicado em: (2012)

Computationally profiling peptide: MHC recognition by T-cell receptors and T-cell receptor-mimetic antibodies
Por: Raybould, MIJ, et al.
Publicado em: (2023)

TCR binding to peptide-MHC stabilizes a flexible recognition interface.
Por: Willcox, B, et al.
Publicado em: (1999)

Mechanical forces impair antigen discrimination by reducing differences in T cell receptor off-rates
Por: Dushek, O
Publicado em: (2022)

Non-catalytic tyrosine-phosphorylated receptors.
Por: Dushek, O, et al.
Publicado em: (2012)

Basic residues in the T-cell receptor ζ cytoplasmic domain mediate membrane association and modulate signaling.
Por: Zhang, H, et al.
Publicado em: (2011)

Computationally profiling peptide:MHC recognition by T-cell receptors and T-cell receptor-mimetic antibodies
Por: Matthew I. J. Raybould, et al.
Publicado em: (2023-01-01)

Systems model of T cell receptor proximal signaling reveals emergent ultrasensitivity
Por: Mukhopadhyay, H, et al.
Publicado em: (2013)

Systems model of T cell receptor proximal signaling reveals emergent ultrasensitivity
Por: Mukhopadhyay, H, et al.
Publicado em: (2013)

CD8 helps TCR catch slippery self pMHC
Por: Dushek, O, et al.
Publicado em: (2018)

Quantifying conformational changes in the TCR:pMHC-I binding interface
Por: McMaster, B, et al.
Publicado em: (2024)

Variable regions of antibodies and T-cell receptors may not be sufficient in molecular simulations investigating binding.
Por: Knapp, B, et al.
Publicado em: (2017)

Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms.
Por: Stewart-Jones, G, et al.
Publicado em: (2012)

Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms.
Por: Stewart-Jones, G, et al.
Publicado em: (2012)

Regulation of temporal cytokine production by co-stimulation receptors in TCR-T cells is lost in CAR-T cells
Por: Patel, A, et al.
Publicado em: (2024)

Intrinsic disorder in the T cell receptor creates cooperativity and controls ZAP70 binding
Por: Clemens, L, et al.
Publicado em: (2020)

Exploring peptide/MHC detachment processes using hierarchical natural move Monte Carlo
Por: Knapp, B, et al.
Publicado em: (2015)

Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics
Por: Barton, MI, et al.
Publicado em: (2021)

Cooperative binding of T cell receptor and CD4 to peptide-MHC enhances antigen sensitivity
Por: Muaz Nik Rushdi, et al.
Publicado em: (2022-11-01)

PeptX: Using Genetic Algorithms to optimize peptides for MHC binding
Por: Ribarics Reiner, et al.
Publicado em: (2011-06-01)

pyHVis3D: Visualising Molecular Simulation deduced H-bond networks in 3D: Application to T-cell receptor interactions
Por: Knapp, B, et al.
Publicado em: (2018)

Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G.
Por: Shiroishi, M, et al.
Publicado em: (2003)

Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules
Por: Georgia F. Papadaki, et al.
Publicado em: (2023-01-01)

NNAlign_MA; MHC peptidome deconvolution for accurate MHC binding motif characterization and improved T-cell epitope predictions
Por: Alvarez, B, et al.
Publicado em: (2019)

Quantifying conformational changes in the TCR:pMHC-I binding interface
Por: Benjamin McMaster, et al.
Publicado em: (2024-12-01)

Elementary steps in T cell receptor triggering.
Por: Dushek, O
Publicado em: (2011)

Homodimerisation of the lymph vessel endothelial receptor LYVE-1 through a redox-labile disulfide is critical for hyaluronan binding in lymphatic endothelium
Por: Banerji, S, et al.
Publicado em: (2016)

Homodimerisation of the lymph vessel endothelial receptor LYVE-1 through a redox-labile disulfide is critical for hyaluronan binding in lymphatic endothelium
Por: Banerji, S, et al.
Publicado em: (2016)

T-cell receptors binding orientation over peptide/MHC class I is driven by long-range interactions.
Por: Mathias Ferber, et al.
Publicado em: (2012-01-01)