GATA3 Mutations Found in Breast Cancers May Be Associated with Aberrant Nuclear Localization, Reduced Transactivation and Cell Invasiveness
Somatic and germline mutations in the dual zinc-finger transcription factor GATA3 are associated with breast cancers expressing the estrogen receptor (ER) and the autosomal dominant hypoparathyroidism-deafness-renal dysplasia syndrome, respectively. To elucidate the role of GATA3 in breast tumorigen...
Glavni autori: | Gaynor, K, Grigorieva, I, Allen, MD, Esapa, C, Head, R, Gopinath, P, Christie, P, Nesbit, M, Jones, J, Thakker, R |
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Format: | Journal article |
Jezik: | English |
Izdano: |
2013
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Slični predmeti
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GATA3 mutations found in breast cancers may be associated with aberrant nuclear localization, reduced transactivation and cell invasiveness.
od: Gaynor, K, i dr.
Izdano: (2013) -
A missense GATA3 mutation, Thr272Ile, causes the hypoparathyroidism, deafness, and renal dysplasia syndrome.
od: Gaynor, K, i dr.
Izdano: (2009) -
Gata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-specific transcription factor Gcm2.
od: Grigorieva, I, i dr.
Izdano: (2010) -
The role of the transcription factor GATA3 in calcium homeostasis and tumourigenesis
od: Gaynor, K, i dr.
Izdano: (2011) -
GATA3 haplo-insufficiency causes human HDR syndrome.
od: Van Esch, H, i dr.
Izdano: (2000)