Expression of dominant-negative src-homology domain 2-containing protein tyrosine phosphatase-1 results in increased Syk tyrosine kinase activity and B cell activation.

The Src-homology domain 2 (SH2)-containing cytoplasmic tyrosine phosphatase, SHP-1 (SH2-containing protein tyrosine phosphatase-1), interacts with several B cell surface and intracellular signal transduction molecules through its SH2 domains. Mice with the motheaten and viable motheaten mutations ar...

詳細記述

書誌詳細
主要な著者: Dustin, L, Plas, DR, Wong, J, Hu, Y, Soto, C, Chan, A, Thomas, M
フォーマット: Journal article
言語:English
出版事項: 1999