Polymorphisms in the catechol-O-methyltransferase (COMT) gene influence plasma total homocysteine levels.

Elevated plasma total homocysteine (tHcy) is a risk factor for various disorders. We investigated whether functional polymorphisms in catechol-O-methyltransferase (COMT) influence tHcy, since COMT activity produces S-adenosylhomocysteine (SAH), a homocysteine precursor. We hypothesized that high act...

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Príomhchruthaitheoirí: Tunbridge, E, Harrison, P, Warden, DR, Johnston, C, Refsum, H, Smith, A
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2008