Accurate reconstruction of insertion-deletion histories by statistical phylogenetics.
The Multiple Sequence Alignment (MSA) is a computational abstraction that represents a partial summary either of indel history, or of structural similarity. Taking the former view (indel history), it is possible to use formal automata theory to generalize the phylogenetic likelihood framework for fi...
Main Authors: | Westesson, O, Lunter, G, Paten, B, Holmes, I |
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Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2012
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