ATM-dependent downregulation of USP7/HAUSP by PPM1G activates p53 response to DNA damage.

ATM-dependent downregulation of USP7/HAUSP by PPM1G activates p53 response to DNA damage.

他のバージョン（1件）を表示する

The deubiquitylation enzyme USP7/HAUSP plays a major role in regulating genome stability and cancer prevention by controlling the key proteins involved in the DNA damage response. Despite this important role in controlling other proteins, USP7 itself has not been recognized as a target for regulatio...

書誌詳細
主要な著者:	Khoronenkova, S, Dianova, I, Ternette, N, Kessler, B, Parsons, J, Dianov, G
フォーマット:	Journal article
言語:	English
出版事項:	2012

類似資料

ATM-Dependent Downregulation of USP7/HAUSP by PPM1G Activates p53 Response to DNA Damage
著者:: Khoronenkova, S, 等
出版事項: (2012)

Regulation of USP7/HAUSP in response to DNA damage: yet another role for ATM.
著者:: Khoronenkova, S, 等
出版事項: (2012)

USP7/HAUSP stimulates repair of oxidative DNA lesions.
著者:: Khoronenkova, S, 等
出版事項: (2011)

USP7/HAUSP promotes the sequence-specific DNA binding activity of p53.
著者:: Feroz Sarkari, 等
出版事項: (2010-09-01)

Phosphorylation of PNKP by ATM prevents its proteasomal degradation and enhances resistance to oxidative stress.
著者:: Parsons, J, 等
出版事項: (2012)

USP7S-dependent inactivation of Mule regulates DNA damage signalling and repair.
著者:: Khoronenkova, S, 等
出版事項: (2013)

Proteome changes induced by knock-down of the deubiquitylating enzyme HAUSP/USP7.
著者:: Kessler, B, 等
出版事項: (2007)

USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA polymerase β.
著者:: Parsons, J, 等
出版事項: (2011)

Structural basis of competitive recognition of p53 and MDM2 by HAUSP/USP7: implications for the regulation of the p53-MDM2 pathway.
著者:: Min Hu, 等
出版事項: (2006-02-01)

ARF induction in response to DNA strand breaks is regulated by PARP1
著者:: Orlando, G, 等
出版事項: (2013)

PE_PGRS38 Interaction With HAUSP Downregulates Antimycobacterial Host Defense via TRAF6
著者:: Jae-Sung Kim, 等
出版事項: (2022-04-01)

DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization
著者:: Stephanie J Papp, 等
出版事項: (2015-03-01)

Phosphorylation of Daxx by ATM contributes to DNA damage-induced p53 activation.
著者:: Jun Tang, 等
出版事項: (2013-01-01)

CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins.
著者:: Parsons, J, 等
出版事項: (2008)

Correction: Phosphorylation of Daxx by ATM Contributes to DNA Damage-Induced p53 Activation
出版事項: (2013-01-01)

Correction: Phosphorylation of Daxx by ATM Contributes to DNA Damage-Induced p53 Activation.
著者:: Jun Tang, 等
出版事項: (2013-01-01)

Ubiquitin ligase ARF-BP1/Mule modulates base excision repair.
著者:: Parsons, J, 等
出版事項: (2009)

End-damage-specific proteins facilitate recruitment or stability of X-ray cross-complementing protein 1 at the sites of DNA single-strand break repair.
著者:: Parsons, J, 等
出版事項: (2005)

APE1-dependent repair of DNA single-strand breaks containing 3'-end 8-oxoguanine.
著者:: Parsons, J, 等
出版事項: (2005)

The DNA damage sensor ATM kinase interacts with the p53 mRNA and guides the DNA damage response pathway
著者:: Konstantinos Karakostis, 等
出版事項: (2024-01-01)

Cellular responses to DNA damage: cell-cycle checkpoints, apoptosis and the roles of p53 and ATM.
著者:: Enoch, T, 等
出版事項: (1995)

DNA polymerase beta promotes recruitment of DNA ligase III alpha-XRCC1 to sites of base excision repair.
著者:: Parsons, J, 等
出版事項: (2005)

USP15 regulates radiation-induced DNA damage and intestinal injury through K48-linked deubiquitination and stabilisation of ATM
著者:: Ruiqiu Zhu, 等
出版事項: (2024-11-01)

The emerging role of Mule and ARF in the regulation of base excision repair.
著者:: Khoronenkova, S, 等
出版事項: (2011)

The emerging role of Mule and ARF in the regulation of base excision repair
著者:: Khoronenkova, S, 等
出版事項: (2011)

Phosphorylation of SIRT7 by ATM causes DNA mismatch repair downregulation and adaptive mutability during chemotherapy
著者:: Lianhui Sun, 等
出版事項: (2025-02-01)

Ubiquitin ligase UBR3 regulates cellular levels of the essential DNA repair protein APE1 and is required for genome stability.
著者:: Meisenberg, C, 等
出版事項: (2012)

Poly(ADP-ribose) polymerase-1 protects excessive DNA strand breaks from deterioration during repair in human cell extracts.
著者:: Parsons, J, 等
出版事項: (2005)

Poly(ADP-ribose) polymerase-1 modulates DNA repair capacity and prevents formation of DNA double strand breaks.
著者:: Woodhouse, B, 等
出版事項: (2008)

ATM and Chk2 kinase target the p53 cofactor Strap.
著者:: Adams, C, 等
出版事項: (2008)

Downregulation of VRK1 by p53 in response to DNA damage is mediated by the autophagic pathway.
著者:: Alberto Valbuena, 等
出版事項: (2011-02-01)

miR-18a impairs DNA damage response through downregulation of ataxia telangiectasia mutated (ATM) kinase.
著者:: Libing Song, 等
出版事項: (2011-01-01)

APE1 is the major 3'-phosphoglycolate activity in human cell extracts.
著者:: Parsons, J, 等
出版事項: (2004)

PPM1G promotes cell proliferation via modulating mutant GOF p53 protein expression in hepatocellular carcinoma
著者:: Wen Hu, 等
出版事項: (2024-03-01)

Monitoring base excision repair proteins on damaged DNA using human cell extracts.
著者:: Parsons, J, 等
出版事項: (2004)

USP7 inhibitors suppress tumour neoangiogenesis and promote synergy with immune checkpoint inhibitors by downregulating fibroblast VEGF
著者:: Anamarija Jurisic, 等
出版事項: (2024-04-01)

USP7 regulates growth and maintains the stemness of p53-mutant colorectal cancer cells via stabilizing of mutant p53
著者:: Xue Li, 等
出版事項: (2024-09-01)

Phosphorylation of the DNA damage repair factor 53BP1 by ATM kinase controls neurodevelopmental programs in cortical brain organoids.
著者:: Bitna Lim, 等
出版事項: (2024-09-01)

Effects of USP7 on radiation sensitivity through p53 pathway in laryngeal squamous cell carcinoma
著者:: Hao Niu, 等
出版事項: (2022-08-01)

Abrogation of USP7 is an alternative strategy to downregulate PD-L1 and sensitize gastric cancer cells to T cells killing
著者:: Zhiru Wang, 等
出版事項: (2021-03-01)