ASYMMETRIC-SYNTHESIS OF THE ENANTIOMERS OF THE DIARYLCARBINOL (1R)-1-(1-HYDROXYPHENYLMETHYL)-2-HYDROXYBENZENE AND (1S)-1-(1-HYDROXYPHENYLMETHYL)-2-HYDROXYBENZENE
(1S)-1-Phenethyl(phenyl chromium tricarbonyl) ether (-)-4 undergoes completely stereoselective ortho-deprotonation with the thus formed carbanion being converted by the complementary sequences, benzoylation/hydride reduction and formylation/PhMgBr addition, to generate after decomplexation and depro...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
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1995
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| _version_ | 1826294917112004608 |
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| author | Davies, S Hume, W |
| author_facet | Davies, S Hume, W |
| author_sort | Davies, S |
| collection | OXFORD |
| description | (1S)-1-Phenethyl(phenyl chromium tricarbonyl) ether (-)-4 undergoes completely stereoselective ortho-deprotonation with the thus formed carbanion being converted by the complementary sequences, benzoylation/hydride reduction and formylation/PhMgBr addition, to generate after decomplexation and deprotection the homochiral diarylcarbinols (-)-(1R)- and (+)-(1S)-1-(1- hydroxyphenylmethyl)-2-hydroxybenzene 1, respectively. |
| first_indexed | 2024-03-07T03:53:05Z |
| format | Journal article |
| id | oxford-uuid:c1f1792b-6d2b-4554-b6b3-7493d9584b45 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T03:53:05Z |
| publishDate | 1995 |
| record_format | dspace |
| spelling | oxford-uuid:c1f1792b-6d2b-4554-b6b3-7493d9584b452022-03-27T06:05:17ZASYMMETRIC-SYNTHESIS OF THE ENANTIOMERS OF THE DIARYLCARBINOL (1R)-1-(1-HYDROXYPHENYLMETHYL)-2-HYDROXYBENZENE AND (1S)-1-(1-HYDROXYPHENYLMETHYL)-2-HYDROXYBENZENEJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:c1f1792b-6d2b-4554-b6b3-7493d9584b45EnglishSymplectic Elements at Oxford1995Davies, SHume, W(1S)-1-Phenethyl(phenyl chromium tricarbonyl) ether (-)-4 undergoes completely stereoselective ortho-deprotonation with the thus formed carbanion being converted by the complementary sequences, benzoylation/hydride reduction and formylation/PhMgBr addition, to generate after decomplexation and deprotection the homochiral diarylcarbinols (-)-(1R)- and (+)-(1S)-1-(1- hydroxyphenylmethyl)-2-hydroxybenzene 1, respectively. |
| spellingShingle | Davies, S Hume, W ASYMMETRIC-SYNTHESIS OF THE ENANTIOMERS OF THE DIARYLCARBINOL (1R)-1-(1-HYDROXYPHENYLMETHYL)-2-HYDROXYBENZENE AND (1S)-1-(1-HYDROXYPHENYLMETHYL)-2-HYDROXYBENZENE |
| title | ASYMMETRIC-SYNTHESIS OF THE ENANTIOMERS OF THE DIARYLCARBINOL (1R)-1-(1-HYDROXYPHENYLMETHYL)-2-HYDROXYBENZENE AND (1S)-1-(1-HYDROXYPHENYLMETHYL)-2-HYDROXYBENZENE |
| title_full | ASYMMETRIC-SYNTHESIS OF THE ENANTIOMERS OF THE DIARYLCARBINOL (1R)-1-(1-HYDROXYPHENYLMETHYL)-2-HYDROXYBENZENE AND (1S)-1-(1-HYDROXYPHENYLMETHYL)-2-HYDROXYBENZENE |
| title_fullStr | ASYMMETRIC-SYNTHESIS OF THE ENANTIOMERS OF THE DIARYLCARBINOL (1R)-1-(1-HYDROXYPHENYLMETHYL)-2-HYDROXYBENZENE AND (1S)-1-(1-HYDROXYPHENYLMETHYL)-2-HYDROXYBENZENE |
| title_full_unstemmed | ASYMMETRIC-SYNTHESIS OF THE ENANTIOMERS OF THE DIARYLCARBINOL (1R)-1-(1-HYDROXYPHENYLMETHYL)-2-HYDROXYBENZENE AND (1S)-1-(1-HYDROXYPHENYLMETHYL)-2-HYDROXYBENZENE |
| title_short | ASYMMETRIC-SYNTHESIS OF THE ENANTIOMERS OF THE DIARYLCARBINOL (1R)-1-(1-HYDROXYPHENYLMETHYL)-2-HYDROXYBENZENE AND (1S)-1-(1-HYDROXYPHENYLMETHYL)-2-HYDROXYBENZENE |
| title_sort | asymmetric synthesis of the enantiomers of the diarylcarbinol 1r 1 1 hydroxyphenylmethyl 2 hydroxybenzene and 1s 1 1 hydroxyphenylmethyl 2 hydroxybenzene |
| work_keys_str_mv | AT daviess asymmetricsynthesisoftheenantiomersofthediarylcarbinol1r11hydroxyphenylmethyl2hydroxybenzeneand1s11hydroxyphenylmethyl2hydroxybenzene AT humew asymmetricsynthesisoftheenantiomersofthediarylcarbinol1r11hydroxyphenylmethyl2hydroxybenzeneand1s11hydroxyphenylmethyl2hydroxybenzene |