Spectrum and prevalence of FP/TMEM127 gene mutations in pheochromocytomas and paragangliomas.

Spectrum and prevalence of FP/TMEM127 gene mutations in pheochromocytomas and paragangliomas.

CONTEXT: Pheochromocytomas and paragangliomas are genetically heterogeneous neural crest-derived neoplasms. We recently identified germline mutations of the novel transmembrane-encoding gene FP/TMEM127 in familial and sporadic pheochromocytomas consistent with a tumor suppressor effect. OBJECTIVES:...

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Manylion Llyfryddiaeth
Prif Awduron: Yao, L, Schiavi, F, Cascon, A, Qin, Y, Inglada-Pérez, L, King, E, Toledo, R, Ercolino, T, Rapizzi, E, Ricketts, C, Mori, L, Giacchè, M, Mendola, A, Taschin, E, Boaretto, F, Loli, P, Iacobone, M, Rossi, G, Biondi, B, Lima-Junior, J, Kater, C, Bex, M, Vikkula, M, Grossman, AB, Gruber, S
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2010

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