Enantioselective organocatalytic Michael addition of malonate esters to nitro olefins using bifunctional cinchonine derivatives.
A family of 9-amino(9-deoxy) epicinchonine derivatives, possessing a range of mono- and bidentate hydrogen bond donor groups at the 9-position, were synthesised and evaluated for asymmetric organocatalytic activity in the dimethyl malonate Michael addition to beta-nitrostyrene; thiourea derivative w...
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| Autori principali: |
Ye, J,
Dixon, D,
Hynes, P |
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| Natura: | Journal article
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| Lingua: | English |
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| Pubblicazione: |
2005
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