Pathways accessory to proteasomal proteolysis are less efficient in major histocompatibility complex class I antigen production.

Degradation of cytosolic proteins depends largely on the proteasome, and a fraction of the cleavage products are presented as major histocompatibility complex (MHC) class I-bound ligands at the cell surface of antigen presenting cells. Proteolytic pathways accessory to the proteasome contribute to p...

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書目詳細資料
Main Authors: Kessler, B, Hong, X, Petrovic, J, Borodovsky, A, Dantuma, N, Bogyo, M, Overkleeft, H, Ploegh, H, Glas, R
格式: Journal article
語言:English
出版: 2003

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