Pathways accessory to proteasomal proteolysis are less efficient in major histocompatibility complex class I antigen production.
Degradation of cytosolic proteins depends largely on the proteasome, and a fraction of the cleavage products are presented as major histocompatibility complex (MHC) class I-bound ligands at the cell surface of antigen presenting cells. Proteolytic pathways accessory to the proteasome contribute to p...
Main Authors: | Kessler, B, Hong, X, Petrovic, J, Borodovsky, A, Dantuma, N, Bogyo, M, Overkleeft, H, Ploegh, H, Glas, R |
---|---|
格式: | Journal article |
語言: | English |
出版: |
2003
|
相似書籍
-
MHC class I antigen processing regulated by cytosolic proteolysis-short cuts that alter peptide generation.
由: Kessler, B, et al.
出版: (2002) -
Integration of the ubiquitin-proteasome pathway with a cytosolic oligopeptidase activity.
由: Wang, E, et al.
出版: (2000) -
A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14.
由: Borodovsky, A, et al.
出版: (2001) -
Dissecting Intracellular Proteolysis Using Small Molecule Inhibitors and Molecular Probes
由: Ovaa, H, et al.
出版: (2007) -
Frequency of Major Histocompatibility Antigens Class I in Mazandaran Province
由: Fatemeh Toghani Hulari, et al.
出版: (2022-04-01)