Tandem copper-catalysed aryl and alkenyl amination reactions: the synthesis of N-functionalised indoles.

A Cu-diamine complex effectively catalyses tandem C-N bond formation on 2-(2-haloalkenyl)-aryl halide substrates, to deliver a series of N-functionalised indoles. Anilines, amides and carbamates are all effective coupling partners under the developed conditions.

Bibliographic Details
Main Authors: Hodgkinson, R, Schulz, J, Willis, M
Format: Journal article
Language:English
Published: 2009
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author Hodgkinson, R
Schulz, J
Willis, M
author_facet Hodgkinson, R
Schulz, J
Willis, M
author_sort Hodgkinson, R
collection OXFORD
description A Cu-diamine complex effectively catalyses tandem C-N bond formation on 2-(2-haloalkenyl)-aryl halide substrates, to deliver a series of N-functionalised indoles. Anilines, amides and carbamates are all effective coupling partners under the developed conditions.
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spelling oxford-uuid:c2451a5c-8aa0-46a3-a930-d4752ad63b472022-03-27T06:07:49ZTandem copper-catalysed aryl and alkenyl amination reactions: the synthesis of N-functionalised indoles.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:c2451a5c-8aa0-46a3-a930-d4752ad63b47EnglishSymplectic Elements at Oxford2009Hodgkinson, RSchulz, JWillis, MA Cu-diamine complex effectively catalyses tandem C-N bond formation on 2-(2-haloalkenyl)-aryl halide substrates, to deliver a series of N-functionalised indoles. Anilines, amides and carbamates are all effective coupling partners under the developed conditions.
spellingShingle Hodgkinson, R
Schulz, J
Willis, M
Tandem copper-catalysed aryl and alkenyl amination reactions: the synthesis of N-functionalised indoles.
title Tandem copper-catalysed aryl and alkenyl amination reactions: the synthesis of N-functionalised indoles.
title_full Tandem copper-catalysed aryl and alkenyl amination reactions: the synthesis of N-functionalised indoles.
title_fullStr Tandem copper-catalysed aryl and alkenyl amination reactions: the synthesis of N-functionalised indoles.
title_full_unstemmed Tandem copper-catalysed aryl and alkenyl amination reactions: the synthesis of N-functionalised indoles.
title_short Tandem copper-catalysed aryl and alkenyl amination reactions: the synthesis of N-functionalised indoles.
title_sort tandem copper catalysed aryl and alkenyl amination reactions the synthesis of n functionalised indoles
work_keys_str_mv AT hodgkinsonr tandemcoppercatalysedarylandalkenylaminationreactionsthesynthesisofnfunctionalisedindoles
AT schulzj tandemcoppercatalysedarylandalkenylaminationreactionsthesynthesisofnfunctionalisedindoles
AT willism tandemcoppercatalysedarylandalkenylaminationreactionsthesynthesisofnfunctionalisedindoles