Synaptic protein CSF levels relate to memory scores in individuals without dementia
Background: We investigated how cerebrospinal fluid levels of synaptic proteins associate with memory function in normal cognition (CN) and mild cognitive impairment (MCI), and investigated the effect of amyloid positivity on these associations. Methods: We included 242 CN (105(43%) abnormal amyloid...
Auteurs principaux: | Wesenhagen, KEJ, de Leeuw, DM, Tomassen, J, Gobom, J, Bos, I, Vos, SJB, Martinez-Lage, P, Tainta, M, Popp, J, Peyratout, G, Tsolaki, M, Vandenberghe, R, Freund-Levi, Y, Verhey, F, Lovestone, S, Streffer, J, Dobricic, V, Blennow, K, Scheltens, P, Smit, AB, Bertram, L, Teunissen, CE, Zetterberg, H, Tijms, BM |
---|---|
Format: | Journal article |
Langue: | English |
Publié: |
BioMed Central
2025
|
Documents similaires
-
CSF proteomic profiles of neurodegeneration biomarkers in Alzheimer's disease
par: Delvenne, A, et autres
Publié: (2024) -
Involvement of the choroid plexus in Alzheimer’s disease pathophysiology: findings from mouse and human proteomic studies
par: Delvenne, A, et autres
Publié: (2024) -
White paper by the Society for CSF Analysis and Clinical Neurochemistry: Overcoming barriers in biomarker development and clinical translation
par: Teunissen, C, et autres
Publié: (2018) -
Validation of plasma proteomic biomarkers relating to brain amyloid burden in the EMIF-Alzheimer's disease multimodal biomarker discovery cohort
par: Westwood, S, et autres
Publié: (2020) -
MRI predictors of amyloid pathology: results from the EMIF-AD multimodal biomarker discovery study
par: ten Kate, M, et autres
Publié: (2018)