SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination

SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination

<p><strong>Background</strong> Most studies of immunity to SARS-CoV-2 focus on circulating antibody, giving limited insights into mucosal defences that prevent viral replication and onward transmission. We studied nasal and plasma antibody responses one year after hospitalisation f...

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Huvudupphovsmän: Liew, F, Talwar, S, Cross, A, Willett, BJ, Scott, S, Logan, N, Siggins, MK, Swieboda, D, Sidhu, JK, Efstathiou, C, Moore, SC, Davis, C, Mohamed, N, Nunag, J, King, C, Thompson, AAR, Rowland-Jones, SL, Docherty, AB, Chalmers, JD, Ho, L-P, Horsley, A, Raman, B, Poinasamy, K, Marks, M, Kon, OM, Howard, L, Wootton, DG, Dunachie, S, Quint, JK, Evans, RA, Wain, LV, Fontanella, S, de Silva, TI, Ho, A, Harrison, E, Baillie, JK, Semple, MG, Brightling, C, Thwaites, RS, Turtle, L, Openshaw, PJM
Övriga upphovsmän: ISARIC4C Investigators
Materialtyp: Journal article
Språk:English
Publicerad: Elsevier 2022

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