VirBR, a transcription regulator, promotes IncX3 plasmid transmission, and persistence of bla NDM-5 in zoonotic bacteria

VirBR, a transcription regulator, promotes IncX3 plasmid transmission, and persistence of bla NDM-5 in zoonotic bacteria

IncX3 plasmids carrying the New Delhi metallo-β-lactamase-encoding gene, blaNDM-5, are rapidly spreading globally in both humans and animals. Given that carbapenems are listed on the WHO AWaRe watch group and are prohibited for use in animals, the drivers for the successful dissemination of Carbapen...

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Bibliographic Details
Main Authors: Ma, T, Xie, N, Gao, Y, Fu, J, Tan, CE, Yang, QE, Wang, S, Shen, Z, Ji, Q, Parkhill, J, Wu, C, Wang, Y, Walsh, TR, Shen, J
Format: Journal article
Language:English
Published: Nature Research 2024

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