Membrane mechanical properties regulate the effect of strain on spontaneous electrophysiology in human iPSC-derived neurons

Peripheral nerves contain neuron fibres vital for movement and sensation and are subject to continuous elongation and compression during everyday movement. At supraphysiological strains conduction blocks occur, resulting in permanent or temporary loss of function. The mechanisms underpinning these a...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Bianchi, F, Pereno, V, George, JH, Thompson, MS, Ye, H
Format: Journal article
Sprache:English
Veröffentlicht: Elsevier 2019