A model-based approach to capture genetic variation for future association studies.

A model-based approach to capture genetic variation for future association studies.

Genome-wide association studies are still constrained by the cost of genotyping. For this reason, the selection of a reduced set of markers or tags able to capture a significant proportion of the genetic variation is an important aspect of these studies. Most tagging SNP selection methods have been...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Eyheramendy, S, Marchini, J, McVean, G, Myers, S, Donnelly, P
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2007

समान संसाधन

A new multipoint method for genome-wide association studies by imputation of genotypes.
द्वारा: Marchini, J, और अन्य
प्रकाशित: (2007)

Estimating recombination rates from genetic variation in humans.
द्वारा: Auton, A, और अन्य
प्रकाशित: (2012)

Estimating meiotic gene conversion rates from population genetic data.
द्वारा: Gay, J, और अन्य
प्रकाशित: (2007)

A common sequence motif associated with recombination hot spots and genome instability in humans.
द्वारा: Myers, S, और अन्य
प्रकाशित: (2008)

A common sequence motif associated with recombination hot spots and genome instability in humans.
द्वारा: Myers, S, और अन्य
प्रकाशित: (2008)

Perspectives on human genetic variation from the HapMap Project.
द्वारा: McVean, G, और अन्य
प्रकाशित: (2005)

Perspectives on human genetic variation from the HapMap project
द्वारा: McVean, G, और अन्य
प्रकाशित: (2005)

Interrogating genetic variation in the HLA using high throughput technologies
द्वारा: McVean, G, और अन्य
प्रकाशित: (2012)

Evolutionary genetics: what is driving male mutation?
द्वारा: McVean, G
प्रकाशित: (2000)

PRDM9 marks the spot.
द्वारा: McVean, G, और अन्य
प्रकाशित: (2010)

Recombination Rates, their local variation and the estimated number of hotspots in the human genome.
द्वारा: Stumpf, M, और अन्य
प्रकाशित: (2003)

A statistical method for predicting classical HLA alleles from SNP data.
द्वारा: Leslie, S, और अन्य
प्रकाशित: (2008)

A fine-scale map of recombination rates and hotspots across the human genome.
द्वारा: Myers, S, और अन्य
प्रकाशित: (2005)

The influence of recombination on human genetic diversity.
द्वारा: Spencer, C, और अन्य
प्रकाशित: (2006)

The influence of recombination on human genetic diversity.
द्वारा: Spencer, C, और अन्य
प्रकाशित: (2006)

Estimating recombination rates from population-genetic data.
द्वारा: Stumpf, M, और अन्य
प्रकाशित: (2003)

A natural encoding of genetic variation in a Burrows-Wheeler Transform to enable mapping and genome inference
द्वारा: Iqbal, Z, और अन्य
प्रकाशित: (2016)

A natural encoding of genetic variation in a Burrows-Wheeler Transform to enable mapping and genome inference
द्वारा: Iqbal, Z, और अन्य
प्रकाशित: (2016)

Elucidating relationships between P.falciparum prevalence and measures of genetic diversity with a combined genetic-epidemiological model of malaria.
द्वारा: Jason A Hendry, और अन्य
प्रकाशित: (2021-08-01)

Trinculo: Bayesian and frequentist multinomial logistic regression for genome-wide association studies of multi-category phenotypes.
द्वारा: Jostins, L, और अन्य
प्रकाशित: (2016)

The structure of linkage disequilibrium around a selective sweep.
द्वारा: McVean, G
प्रकाशित: (2007)

What drives recombination hotspots to repeat DNA in humans?
द्वारा: McVean, G
प्रकाशित: (2010)

A genealogical interpretation of principal components analysis.
द्वारा: McVean, G
प्रकाशित: (2009)

Linkage Disequilibrium, Recombination and Selection
द्वारा: McVean, G
प्रकाशित: (2008)

The fine-scale structure of recombination rate variation in the human genome.
द्वारा: Mcvean, G, और अन्य
प्रकाशित: (2004)

The impact of age on genetic risk for common diseases
द्वारा: Jiang, X, और अन्य
प्रकाशित: (2021)

The impact of age on genetic risk for common diseases.
द्वारा: Xilin Jiang, और अन्य
प्रकाशित: (2021-08-01)

The distribution and causes of meiotic recombination in the human genome.
द्वारा: Myers, S, और अन्य
प्रकाशित: (2006)

Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank
द्वारा: Cortes, A, और अन्य
प्रकाशित: (2017)

An integrated map of genetic variation from 1,092 human genomes.
द्वारा: Abecasis, G, और अन्य
प्रकाशित: (2012)

Genomewide association studies and common disease--realizing clinical utility.
द्वारा: Fugger, L, और अन्य
प्रकाशित: (2012)

Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination.
द्वारा: Myers, S, और अन्य
प्रकाशित: (2010)

The influence of mutation, recombination, population history, and selection on patterns of genetic diversity in Neisseria meningitidis.
द्वारा: Jolley, K, और अन्य
प्रकाशित: (2005)

Graphical model selection for Gaussian conditional random fields in the presence of latent variables
द्वारा: Frot, B, और अन्य
प्रकाशित: (2018)

A coalescent-based method for detecting and estimating recombination from gene sequences.
द्वारा: McVean, G, और अन्य
प्रकाशित: (2002)

Recombination rate estimation in the presence of hotspots.
द्वारा: Auton, A, और अन्य
प्रकाशित: (2007)

A structured ancestral population for the evolution of modern humans.
द्वारा: Harding, R, और अन्य
प्रकाशित: (2004)

Differential confounding of rare and common variants in spatially structured populations
द्वारा: Mathieson, I, और अन्य
प्रकाशित: (2012)

Estimating Selection Coefficients in Spatially Structured Populations from Time Series Data of Allele Frequencies
द्वारा: Mathieson, I, और अन्य
प्रकाशित: (2013)

Estimating diversifying selection and functional constraint in the presence of recombination.
द्वारा: Wilson, D, और अन्य
प्रकाशित: (2006)