Yeast mannan genetics controls the molecular specificity of anti-carbohydrate antibodies cross-reactive to the HIV envelope

Yeast mannan genetics controls the molecular specificity of anti-carbohydrate antibodies cross-reactive to the HIV envelope

Immunologically self carbohydrates protect the human immunodeficiency virus type -1 (HIV-1) surface glycoprotein, gp120 from antibody recognition. However, one broadly neutralising antibody, 2G12, can protect against primary viral challenge by direct recognition of these "self" glycans on...

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Bibliographic Details
Main Authors:	Dunlop, D, Mansab, F, Doores, K, Zitzmann, N, Smith, D, Burton, D, Dwek, R, Scanlan, C
Format:	Conference item
Published:	BioMed Central 2009

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