Optogenetically engineered neurons differentiated from human SH-SY5Y cells survived and expressed ChR2 in 3D hydrogel

The cases of brain degenerative disease will rise as the human population ages. Current treatments have a transient effect and lack an investigative system that is physiologically relevant for testing. There is evidence suggesting optogenetic stimulation is a potential strategy; however, an in vitro...

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Main Authors: Lee, S-Y, George, J, Nagel, D, Ye, H, Seymour, L
格式: Journal article
语言:English
出版: MDPI 2022