Clostridium difficile in England: can we stop washing our hands?
Dingle and colleagues1 provide compelling evidence that the substantial decline in Clostridium difficile infection in England since 2006 resulted from the disappearance of fluoroquinolone-resistant isolates. However, attribution of this decline to specific control measures rests on a false premise....
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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Lancet
2017
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| _version_ | 1797093210304020480 |
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| author | van Kleef, E Kuijper, E Bonten, M Cooper, B |
| author_facet | van Kleef, E Kuijper, E Bonten, M Cooper, B |
| author_sort | van Kleef, E |
| collection | OXFORD |
| description | Dingle and colleagues1 provide compelling evidence that the substantial decline in Clostridium difficile infection in England since 2006 resulted from the disappearance of fluoroquinolone-resistant isolates. However, attribution of this decline to specific control measures rests on a false premise. The authors state that “if decreases in Clostridium difficile infection were driven by improvements in hospital infection control, then transmitted (secondary) cases should decline regardless of susceptibility”.1 In fact, non-specific hospital infection control measures such as hand hygiene, environmental cleaning, and patient isolation will have a disproportionate effect on resistant strains, provided these strains spread preferentially in the hospital setting. |
| first_indexed | 2024-03-07T03:57:01Z |
| format | Journal article |
| id | oxford-uuid:c3397654-346d-4acf-99d2-d741868576e3 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T03:57:01Z |
| publishDate | 2017 |
| publisher | Lancet |
| record_format | dspace |
| spelling | oxford-uuid:c3397654-346d-4acf-99d2-d741868576e32022-03-27T06:14:47ZClostridium difficile in England: can we stop washing our hands?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:c3397654-346d-4acf-99d2-d741868576e3EnglishSymplectic Elements at OxfordLancet2017van Kleef, EKuijper, EBonten, MCooper, BDingle and colleagues1 provide compelling evidence that the substantial decline in Clostridium difficile infection in England since 2006 resulted from the disappearance of fluoroquinolone-resistant isolates. However, attribution of this decline to specific control measures rests on a false premise. The authors state that “if decreases in Clostridium difficile infection were driven by improvements in hospital infection control, then transmitted (secondary) cases should decline regardless of susceptibility”.1 In fact, non-specific hospital infection control measures such as hand hygiene, environmental cleaning, and patient isolation will have a disproportionate effect on resistant strains, provided these strains spread preferentially in the hospital setting. |
| spellingShingle | van Kleef, E Kuijper, E Bonten, M Cooper, B Clostridium difficile in England: can we stop washing our hands? |
| title | Clostridium difficile in England: can we stop washing our hands? |
| title_full | Clostridium difficile in England: can we stop washing our hands? |
| title_fullStr | Clostridium difficile in England: can we stop washing our hands? |
| title_full_unstemmed | Clostridium difficile in England: can we stop washing our hands? |
| title_short | Clostridium difficile in England: can we stop washing our hands? |
| title_sort | clostridium difficile in england can we stop washing our hands |
| work_keys_str_mv | AT vankleefe clostridiumdifficileinenglandcanwestopwashingourhands AT kuijpere clostridiumdifficileinenglandcanwestopwashingourhands AT bontenm clostridiumdifficileinenglandcanwestopwashingourhands AT cooperb clostridiumdifficileinenglandcanwestopwashingourhands |