Fluorochemicals from fluorspar via a phosphate-enabled mechanochemical process that bypasses HF
<p>All fluorochemicals—including elemental fluorine and nucleophilic, electrophilic, and radical fluorinating reagents—are prepared from hydrogen fluoride (HF). This highly toxic and corrosive gas is produced by the reaction of acid-grade fluorspar (>97% CaF<sub&g...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
American Association for the Advancement of Science
2023
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| _version_ | 1826310440479621120 |
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| author | Patel, C André-Joyaux, E Leitch, JA de Irujo-Labalde, XM Ibba, F Struijs, J Ellwanger, MA Paton, R Browne, DL Pupo, G Aldridge, S Hayward, MA Gouverneur, V |
| author_facet | Patel, C André-Joyaux, E Leitch, JA de Irujo-Labalde, XM Ibba, F Struijs, J Ellwanger, MA Paton, R Browne, DL Pupo, G Aldridge, S Hayward, MA Gouverneur, V |
| author_sort | Patel, C |
| collection | OXFORD |
| description | <p>All fluorochemicals—including elemental fluorine and nucleophilic, electrophilic, and radical fluorinating reagents—are prepared from hydrogen fluoride (HF). This highly toxic and corrosive gas is produced by the reaction of acid-grade fluorspar (>97% CaF<sub>2</sub>) with sulfuric acid under harsh conditions. The use of fluorspar to produce fluorochemicals via a process that bypasses HF is highly desirable but remains an unsolved problem because of the prohibitive insolubility of CaF<sub>2</sub>. Inspired by calcium phosphate biomineralization, we herein disclose a protocol of treating acid-grade fluorspar with dipotassium hydrogen phosphate (K<sub>2</sub>HPO<sub>4</sub>) under mechanochemical conditions. The process affords a solid composed of crystalline K<sub>3</sub>(HPO<sub>4</sub>)F and K<sub>2−</sub><em><sub>x</sub></em>Ca<em><sub>y</sub></em>(PO<sub>3</sub>F)<em><sub>a</sub></em>(PO<sub>4</sub>)<em><sub>b</sub></em>, which is found suitable for forging sulfur-fluorine and carbon-fluorine bonds.</p> |
| first_indexed | 2024-03-07T07:52:06Z |
| format | Journal article |
| id | oxford-uuid:c33d0be5-b6e7-4513-a5f8-002989384972 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T07:52:06Z |
| publishDate | 2023 |
| publisher | American Association for the Advancement of Science |
| record_format | dspace |
| spelling | oxford-uuid:c33d0be5-b6e7-4513-a5f8-0029893849722023-07-24T06:52:16ZFluorochemicals from fluorspar via a phosphate-enabled mechanochemical process that bypasses HFJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:c33d0be5-b6e7-4513-a5f8-002989384972EnglishSymplectic ElementsAmerican Association for the Advancement of Science2023Patel, CAndré-Joyaux, ELeitch, JAde Irujo-Labalde, XMIbba, FStruijs, JEllwanger, MAPaton, RBrowne, DLPupo, GAldridge, SHayward, MAGouverneur, V<p>All fluorochemicals—including elemental fluorine and nucleophilic, electrophilic, and radical fluorinating reagents—are prepared from hydrogen fluoride (HF). This highly toxic and corrosive gas is produced by the reaction of acid-grade fluorspar (>97% CaF<sub>2</sub>) with sulfuric acid under harsh conditions. The use of fluorspar to produce fluorochemicals via a process that bypasses HF is highly desirable but remains an unsolved problem because of the prohibitive insolubility of CaF<sub>2</sub>. Inspired by calcium phosphate biomineralization, we herein disclose a protocol of treating acid-grade fluorspar with dipotassium hydrogen phosphate (K<sub>2</sub>HPO<sub>4</sub>) under mechanochemical conditions. The process affords a solid composed of crystalline K<sub>3</sub>(HPO<sub>4</sub>)F and K<sub>2−</sub><em><sub>x</sub></em>Ca<em><sub>y</sub></em>(PO<sub>3</sub>F)<em><sub>a</sub></em>(PO<sub>4</sub>)<em><sub>b</sub></em>, which is found suitable for forging sulfur-fluorine and carbon-fluorine bonds.</p> |
| spellingShingle | Patel, C André-Joyaux, E Leitch, JA de Irujo-Labalde, XM Ibba, F Struijs, J Ellwanger, MA Paton, R Browne, DL Pupo, G Aldridge, S Hayward, MA Gouverneur, V Fluorochemicals from fluorspar via a phosphate-enabled mechanochemical process that bypasses HF |
| title | Fluorochemicals from fluorspar via a phosphate-enabled mechanochemical process that bypasses HF |
| title_full | Fluorochemicals from fluorspar via a phosphate-enabled mechanochemical process that bypasses HF |
| title_fullStr | Fluorochemicals from fluorspar via a phosphate-enabled mechanochemical process that bypasses HF |
| title_full_unstemmed | Fluorochemicals from fluorspar via a phosphate-enabled mechanochemical process that bypasses HF |
| title_short | Fluorochemicals from fluorspar via a phosphate-enabled mechanochemical process that bypasses HF |
| title_sort | fluorochemicals from fluorspar via a phosphate enabled mechanochemical process that bypasses hf |
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