A 2'-alkynylnucleotide strategy for site-directed spin labelling of DNA
<p>This thesis describes the synthesis of derivatives of 2'-ethynyl-2'-deoxynucleosides, and their conversion into phosphoramidite building blocks for DNA synthesis. Herein is also outlined the preparation of azide-bearing nitroxyl radicals. After site-selective incorporation of 2�...
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| Format: | Thèse |
| Langue: | English |
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2016
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