DNA sequence recognition by an imidazole-containing isopropyl-substituted thiazole polyamide (thiazotropsin B).

DNA sequence recognition by an imidazole-containing isopropyl-substituted thiazole polyamide (thiazotropsin B).

We have used DNA footprinting and fluorescence melting experiments to study the sequence specific binding of an imidazole-containing isopropyl-substituted thiazole polyamide (thiazotropsin B) to DNA. While the parent compound (thiazotropsin A) binds to the hexanucleotide sequence ACTAGT, changing on...

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Bibliographic Details
Main Authors:	Hampshire, A, Khairallah, H, Khalaf, A, Ebrahimabadi, A, Waigh, R, Suckling, C, Brown, T, Fox, K
Format:	Journal article
Language:	English
Published:	2006

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