Oncogenic CALR mutant C-terminus mediates dual binding to the thrombopoietin receptor triggering complex dimerization and activation

Míreanna comhchosúla

• Constitutive activation and oncogenicity are mediated by loss of helical structure at the cytosolic boundary of thrombopoietin receptor mutant dimers
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  Foilsithe / Cruthaithe: (2023)
• Application of heteroduplex analysis for CALR mutation screening detection in patients with Ph-myeloproliferative neoplasms
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  Foilsithe / Cruthaithe: (2021-06-01)
• The characteristics of CALR mutations in myeloproliferative neoplasms: a clinical experience from a tertiary care center in Qatar and a literature review
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  Foilsithe / Cruthaithe: (2024-12-01)
• Thrombopoietin, the Primary Regulator of Platelet Production: From Mythos to Logos, a Thirty-Year Journey
  de réir: Kenneth Kaushansky
  Foilsithe / Cruthaithe: (2024-04-01)
• CLINICAL AND LABORATORY FEATURES OF ESSENTIAL THROMBOCYTOSIS AND PRIMARY MYELOFIBROSIS DEPENDING ON JAK2 AND CALR1 MUTATION STATUS
  de réir: E. G. lisina, et al.
  Foilsithe / Cruthaithe: (2017-10-01)