Mosaic loss of chromosome Y in blood is associated with Alzheimer disease

Men have a shorter life expectancy compared with women but the underlying factor(s) are not clear. Late-onset, sporadic Alzheimer disease (AD) is a common and lethal neurodegenerative disorder and many germline inherited variants have been found to influence the risk of developing AD. Our previous r...

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Hlavní autoři: Dumanski, J, Lambert, J, Rasi, C, Giedraitis, V, Davies, H, Grenier-Boley, B, Lindgren, C, Campion, D, Dufouil, C, Pasquier, F, Amouyel, P, Lannfelt, L, Ingelsson, M, Kilander, L, Lind, L, Forsberg, L
Médium: Journal article
Jazyk:English
Vydáno: Cell Press 2016