Predicting antibody complementarity determining region structures without classification.

Antibodies are used extensively in medical and biological research. Their complementarity determining regions (CDRs) define the majority of their antigen binding functionality. CDR structures have been intensively studied and classified (canonical structures). Here we show that CDR structure predict...

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Hlavní autoři: Choi, Y, Deane, C
Médium: Journal article
Jazyk:English
Vydáno: 2011