Predicting antibody complementarity determining region structures without classification.
Antibodies are used extensively in medical and biological research. Their complementarity determining regions (CDRs) define the majority of their antigen binding functionality. CDR structures have been intensively studied and classified (canonical structures). Here we show that CDR structure predict...
Main Authors: | Choi, Y, Deane, C |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2011
|
Similar Items
-
Understanding the impacts of dual methionine oxidations in complementarity-determining regions on the structure of monoclonal antibodies
by: Bo Zhao, et al.
Published: (2024-12-01) -
Deciphering the antigen specificities of antibodies by clustering their complementarity determining region sequences
by: Dianita S. Saputri, et al.
Published: (2023-12-01) -
Antibody complementarity determining region design using high-capacity machine learning
by: Liu, Ge, et al.
Published: (2021) -
A complete, multi-level conformational clustering of antibody complementarity-determining regions
by: Dimitris Nikoloudis, et al.
Published: (2014-07-01) -
Contributions of the complementarity determining regions to the thermal stability of a single-domain antibody.
by: Dan Zabetakis, et al.
Published: (2013-01-01)