Predicting antibody complementarity determining region structures without classification.
Antibodies are used extensively in medical and biological research. Their complementarity determining regions (CDRs) define the majority of their antigen binding functionality. CDR structures have been intensively studied and classified (canonical structures). Here we show that CDR structure predict...
Автори: | Choi, Y, Deane, C |
---|---|
Формат: | Journal article |
Мова: | English |
Опубліковано: |
2011
|
Схожі ресурси
Схожі ресурси
-
Understanding the impacts of dual methionine oxidations in complementarity-determining regions on the structure of monoclonal antibodies
за авторством: Bo Zhao, та інші
Опубліковано: (2024-12-01) -
Deciphering the antigen specificities of antibodies by clustering their complementarity determining region sequences
за авторством: Dianita S. Saputri, та інші
Опубліковано: (2023-12-01) -
Antibody complementarity determining region design using high-capacity machine learning
за авторством: Liu, Ge, та інші
Опубліковано: (2021) -
A complete, multi-level conformational clustering of antibody complementarity-determining regions
за авторством: Dimitris Nikoloudis, та інші
Опубліковано: (2014-07-01) -
Contributions of the complementarity determining regions to the thermal stability of a single-domain antibody.
за авторством: Dan Zabetakis, та інші
Опубліковано: (2013-01-01)