Disruption of coronin 1 signaling in T cells promotes allograft tolerance while maintaining anti-pathogen immunity
The ability of the immune system to discriminate self from non-self is essential for eradicating microbial pathogens but is also responsible for allograft rejection. Whether it is possible to selectively suppress alloresponses while maintaining anti-pathogen immunity remains unknown. We found that m...
Main Authors: | Jayachandran, R, Gumienny, A, Bolinger, B, Ruehl, S, Lang, M, Fucile, G, Mazumder, S, Tchang, V, Woischnig, A, Stiess, M, Kunz, G, Claudi, B, Schmaler, M, Siegmund, K, Li, J, Dertschnig, S, Holländer, G, Medina, E, Karrer, U, Moshous, D, Bumann, D, Khanna, N, Rossi, S, Pieters, J |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2019
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