Reduced cholinergic function in normal and Alzheimer's disease brain is associated with apolipoprotein E4 genotype.

Reduced cholinergic function in normal and Alzheimer's disease brain is associated with apolipoprotein E4 genotype.

Apolipoprotein E (ApoE) is a potent risk factor for Alzheimer's disease. Since the loss of cholinergic function in Alzheimer's disease is known to occur at an early stage in the disease we have examined this function in normal subjects with an Apoepsilon4 allele to see if the deficit occur...

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Manylion Llyfryddiaeth
Prif Awduron:	Allen, S, MacGowan, S, Tyler, S, Wilcock, G, Robertson, A, Holden, P, Smith, S, Dawbarn, D
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	1997

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gan: Treanor, J, et al.
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gan: Allen, S, et al.
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gan: Lovestone, S, et al.
Cyhoeddwyd: (1996)

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gan: Dawbarn, D, et al.
Cyhoeddwyd: (1990)

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gan: Tyler, S, et al.
Cyhoeddwyd: (2003)

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Cyhoeddwyd: (2002)

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gan: Goedert, M, et al.
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gan: Bennet, A, et al.
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gan: Allen, S, et al.
Cyhoeddwyd: (1988)

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gan: Allen, S, et al.
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gan: Bowen, D, et al.
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gan: Pearson, R, et al.
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gan: Wilcock, G, et al.
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gan: Hogervorst, E, et al.
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Cyhoeddwyd: (1999)

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Cyhoeddwyd: (1991)

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