Reduced cholinergic function in normal and Alzheimer's disease brain is associated with apolipoprotein E4 genotype.
Apolipoprotein E (ApoE) is a potent risk factor for Alzheimer's disease. Since the loss of cholinergic function in Alzheimer's disease is known to occur at an early stage in the disease we have examined this function in normal subjects with an Apoepsilon4 allele to see if the deficit occur...
المؤلفون الرئيسيون: | Allen, S, MacGowan, S, Tyler, S, Wilcock, G, Robertson, A, Holden, P, Smith, S, Dawbarn, D |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
1997
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مواد مشابهة
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Effect of gender and apolipoprotein E genotype on response to anticholinesterase therapy in Alzheimer's disease.
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Low affinity nerve growth factor receptor binding in normal and Alzheimer's disease basal forebrain.
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