Reduced cholinergic function in normal and Alzheimer's disease brain is associated with apolipoprotein E4 genotype.

Reduced cholinergic function in normal and Alzheimer's disease brain is associated with apolipoprotein E4 genotype.

Apolipoprotein E (ApoE) is a potent risk factor for Alzheimer's disease. Since the loss of cholinergic function in Alzheimer's disease is known to occur at an early stage in the disease we have examined this function in normal subjects with an Apoepsilon4 allele to see if the deficit occur...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Allen, S, MacGowan, S, Tyler, S, Wilcock, G, Robertson, A, Holden, P, Smith, S, Dawbarn, D
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	1997

Παρόμοια τεκμήρια

Effect of gender and apolipoprotein E genotype on response to anticholinesterase therapy in Alzheimer's disease.
ανά: MacGowan, S, κ.ά.
Έκδοση: (1998)

Quantitative morphometric analysis of basal forebrain neurons expressing β-nerve growth factor receptors in normal and Alzheimer's disease brains
ανά: Allen, S, κ.ά.
Έκδοση: (1990)

Low affinity nerve growth factor receptor binding in normal and Alzheimer's disease basal forebrain.
ανά: Treanor, J, κ.ά.
Έκδοση: (1991)

Normal beta-NGF content in Alzheimer's disease cerebral cortex and hippocampus.
ανά: Allen, S, κ.ά.
Έκδοση: (1991)

Alzheimer's disease, herpes virus in brain, apolipoprotein E4 and herpes labialis
ανά: Lin, W, κ.ά.
Έκδοση: (1998)

NERVE GROWTH-FACTOR RECEPTOR-BINDING IN NORMAL AND ALZHEIMERS-DISEASE BASAL FOREBRAIN
ανά: Treanor, J, κ.ά.
Έκδοση: (1990)

Alzheimer's disease, herpes virus in the brain, apolipoprotein E4 and herpes labialis. (vol 1, pg 173, 1998)
ανά: Lin, W, κ.ά.
Έκδοση: (1998)

The -491A/T polymorphism of the Apolipoprotein E gene is associated with the ApoEepsilon4 allele and Alzheimer's disease.
ανά: Ahmed, A, κ.ά.
Έκδοση: (1999)

DISTRIBUTION OF NGF RECEPTORS IN CONTROL AND ALZHEIMERS-DISEASE BASAL FOREBRAIN
ανά: Dawbarn, D, κ.ά.
Έκδοση: (1990)

Cloning of a non-catalytic form of human trkB and distribution of messenger RNA for trkB in human brain.
ανά: Allen, S, κ.ά.
Έκδοση: (1994)

Changes in alpha- and beta-secretase in Alzheimer's disease
ανά: Tyler, S, κ.ά.
Έκδοση: (2003)

alpha- and beta-secretase: profound changes in Alzheimer's disease.
ανά: Tyler, S, κ.ά.
Έκδοση: (2002)

Treatment of the cholinergic impairment in Alzheimer's disease
ανά: Wilcock, G
Έκδοση: (1994)

Apolipoprotein E genotyping in Alzheimer's disease. The UK Alzheimer's Disease Genetic consortium.
ανά: Lovestone, S, κ.ά.
Έκδοση: (1996)

Nerve growth factor receptor mRNA distribution in human brain: normal levels in basal forebrain in Alzheimer's disease.
ανά: Goedert, M, κ.ά.
Έκδοση: (1989)

Morphometric immunochemical analysis of neurons in the nucleus basalis of Meynert in Alzheimer's disease.
ανά: Allen, S, κ.ά.
Έκδοση: (1988)

Profound and selective loss of catalytic TrkB immunoreactivity in Alzheimer's disease.
ανά: Allen, S, κ.ά.
Έκδοση: (1999)

HLA-DR3 and DQA1*0401: possible risk factors in Alzheimer's disease
ανά: Culpan, D, κ.ά.
Έκδοση: (1999)

The expression of the anti-inflammatory cytokine IL-10 in Alzheimer's disease is independent of IL-10 promoter polymorphisms
ανά: Culpan, D, κ.ά.
Έκδοση: (2002)

Recombinant human nerve growth factor for clinical trials: protein expression, purification, stability and characterisation of binding to infusion pumps.
ανά: Allen, S, κ.ά.
Έκδοση: (2001)

NERVE GROWTH-FACTOR AND OTHER NEUROTROPHINS IN ALZHEIMERS-DISEASE
ανά: Wilcock, G, κ.ά.
Έκδοση: (1994)

Oxidative Insults Are Associated with Apolipoprotein E Genotype in Alzheimer's Disease Brain
ανά: Charles Ramassamy, κ.ά.
Έκδοση: (2000-02-01)

The cholinergic hypothesis of Alzheimer's disease: a review of progress.
ανά: Francis, P, κ.ά.
Έκδοση: (1999)

The blood-brain barrier models to study apolipoprotein E genotypes in Alzheimer’s disease
ανά: Irundika HK Dias, κ.ά.
Έκδοση: (2022-01-01)

The cholinergic hypothesis of Alzheimer's disease: a review of progress - Reply
ανά: Francis, P, κ.ά.
Έκδοση: (1999)

Herpes Simplex Virus Type 1 in the Brain, Apolipoprotein E Genotype and Alzheimer’s Disease
ανά: Uwe Beffert, κ.ά.
Έκδοση: (2020-12-01)

Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease.
ανά: Bowen, D, κ.ά.
Έκδοση: (1983)

Immunoglobulin-like domains define the nerve growth factor binding site of the TrkA receptor.
ανά: Holden, P, κ.ά.
Έκδοση: (1997)

Apolipoprotein E genotype, vitamin E, and Alzheimer’s disease prevention
ανά: P. Huebbe, κ.ά.
Έκδοση: (2012-11-01)

Persistence of cholinergic neurons in the basal nucleus in a brain with senile dementia of the Alzheimer's type demonstrated by immunohistochemical staining for choline acetyltransferase.
ανά: Pearson, R, κ.ά.
Έκδοση: (1983)

Apolipoprotein C-I Expression in the Brain in Alzheimer's Disease
ανά: Caroline Petit-Turcotte, κ.ά.
Έκδοση: (2001-12-01)

The effects of apolipoprotein E genotype, α‐synuclein deficiency, and sex on brain synaptic and Alzheimer's disease–related pathology
ανά: Roni Bar, κ.ά.
Έκδοση: (2018-01-01)

Brain tissue banks in psychiatric and neurological research.
ανά: Wilcock, G, κ.ά.
Έκδοση: (1997)

Role of Cholinergic Signaling in Alzheimer’s Disease
ανά: Zhi-Ru Chen, κ.ά.
Έκδοση: (2022-03-01)

Alzheimer′s disease, anesthesia and the cholinergic system
ανά: Mukul C Kapoor
Έκδοση: (2011-01-01)

Effects of Sex, Age, and Apolipoprotein E Genotype on Brain Ceramides and Sphingosine-1-Phosphate in Alzheimer’s Disease and Control Mice
ανά: Sandra den Hoedt, κ.ά.
Έκδοση: (2021-10-01)

Apolipoprotein E and oxidative stress in brain with relevance to Alzheimer's disease
ανά: D. Allan Butterfield, κ.ά.
Έκδοση: (2020-05-01)

Apolipoproteins and Alzheimer's pathophysiology
ανά: Manja Koch, κ.ά.
Έκδοση: (2018-01-01)

Brain Cholinergic Mechanisms
ανά: Sukumar eVijayaraghavan, κ.ά.
Έκδοση: (2015-09-01)

Latent herpes simplex virus type 1 in normal and Alzheimer's disease brains.
ανά: Jamieson, G, κ.ά.
Έκδοση: (1991)